Amfipoli was an ancient town built in east Macedonia by the river Strimonas, on the spot where earlier town Ennea Odoi used to be, or somewhere very close to it.

Amfipoli was found by the Athenians in 437 B.C. in order to control the mines in Thrace, but the Spartans took hold of it during the first period of the Peloponnesian Wars, in 431-421 B.C.

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